Lakeside 8-bedroom Retreat on Thompson Lake in Otisfield, Maine | House in Otisfield

Nestled along the peaceful shores of Thompson Lake in Otisfield, Maine, 25 Panacea is a private lakeside retreat that blends comfort with natural beauty. Designed for large family gatherings, the property offers expansive shared spaces alongside quiet areas for relaxation.
The property includes a three-level main home with six bedrooms and a two-bedroom apartment above the detached garage. For larger groups, inquire about the neighboring 35 Panacea.
The main house features four king bedrooms—three with en suite baths and twin daybeds—plus one room with two full beds and another with a queen. A finished lower level adds flexibility with two queen pull-out sofas.
The separate apartment offers additional space with two king beds, one queen bed, a full bath, and a kitchen with dining.
A wraparound porch overlooks the lake, creating an ideal spot for morning coffee. Just steps away, the lake offers a sandy-bottom shoreline where guests enjoy a private dock, swim raft, canoe, and kayaks. Boat rentals are available nearby for tubing, skiing, or cruising. Outdoor games like cornhole, ping pong, and bocce provide easy entertainment.
Inside, the kitchen is fully equipped with double ovens, gas and electric cooktops, and a large island. It opens to a dining area with seating for 12, expandable to 20+, and multiple living spaces designed for gathering or unwinding.
Evenings are best spent around a fire under a clear, star-filled sky. The home includes Smart TVs that allow you to login into your favorite streaming apps, a pool table and a great selection of games.
Beyond the property, Portland is a short drive away, offering shops and restaurants. Closer to home, enjoy antiquing, gemstone mining, Oxbow Beer Garden or picking up fresh lobsters from Smedberg’s.
Amenities:
Location & Outdoor Features:
Lakefront property on Thompson Lake
Private setting surrounded by trees
Private T-dock
Floating swim-up raft
Wraparound porch with rocking chairs
Screened-in porches
Outdoor seating areas
Solo Stove
Outdoor games: cornhole, bocce ball, ping pong
Water Activities:
Swimming
Canoe
Kayaks
Fishing
Nearby boat rentals (Thompson Lake Marina)
Kitchen & Dining:
Fully equipped gourmet kitchen
Double ovens
Gas and electric stovetops
2 refrigerators
2 beverage refrigerators
Microwave, dishwasher
Coffee maker
Large kitchen island (seats 4)
Dining table (seats 12, expands to 20+)
Living & Entertainment:
Multiple living areas
Wood stove
2 TV rooms with Smart TV's
3 bedrooms with TV's
Pool table
Board games and card games
High-speed Wi-Fi
Bedrooms & Bathrooms:
First Floor:
Bedroom 1- King bed, ensuite bathroom (shower) shared with common areas, private screened-in porch connected to front porch.
Second Floor:
Bedroom 2- (Master) King bed, twin daybed, TV, private ensuite bathroom with duel shower heads, expansive view of the Lake
Bedroom 3- 2 double beds, Lakeside
Bedroom 4- Queen bed facing driveway.
Second Floor Bath- Oversized bathtub and single shower.
Basement:
Bedroom 5- King bed, twin daybed, Smart TV, ensuite bathroom with Kohler heated Airtub/ shower combo, bathroom shared with common area.
Bedroom 6- King bed, twin daybed, Smart TV
Additional Sleeping in Basement TV room- 2 queen pull out sofa beds.
Apartment Above Garage:
Bedroom 1: King bed
Bedroom 2: Queen bed
King bed in Living Area
Bathroom with single shower
Fitness & Wellness:
Peloton bike
Treadmill
Free weights
Essentials:
Washer and dryer
Heating
Parking on site
Family-friendly

Lakeside 8-bedroom Retreat on Thompson Lake in Otisfield, Maine is located in Oxford. Lakeside 8-bedroom Retreat on Thompson Lake in Otisfield, Maine provides accommodation, featuring Designated Smoking Area, TV, Fireplace/Heating, among other amenities. This House features Designated Smoking Area, TV, Fireplace/Heating, to make your stay a comfortable one.

Lakeside 8-bedroom Retreat on Thompson Lake in Otisfield, Maine has 9 Bedrooms , 4 Bathrooms, and max occupancy of 25 people. The minimum rental for this property is 1 nights, but this can change depending on the season you plan on staying. Previous guests have given good rated it, and VRBO labeled it a top-rated House because of the excellent services rendered by the owner or manager of this House, and has consistently provided great experiences for their guests. Most families or guests that use it recommend it to their friends and some of them are repeat guests. House has a friendly neighborhood, and the Oxford has interesting places to visit. If you want to learn more about the House in Oxford, such as places to visit and things to do nearby, you can check below to learn more.